El-Hadary turned 44 on Sunday and came on in the first half after an injury to Ahmed El-Shenawy, who collided with the post following Moussa Marega’s cross.
Arsenal’s Mohamed Elneny wasted two first-half chances for Egypt, striking over and hitting an effort wide.
Osmane Coulibaly headed over from close range for Mali late on.
The results leaves Egypt second in Group D behind Ghana, who beat Uganda 1-0.
Veteran goalkeeper goes on
Legendary Egyptian goalkeeper El-Hadary was on the bench for the game, but got the call for his 148th cap after El-Shenawy’s unfortunate injury.
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